THE PURPOSE OF THE COURSE

This course focuses on an introduction to clinical laboratory techniques and procedures, lab safety plus quality control measures. Organ system functions like renal and liver will also be covered. Proteins, lipids, carbohydrates and amino acids body constituents will be covered. Prerequisite: CHEM 102

COURSE DESCRIPTION

Introduction to Clinical Laboratory procedures, lab safety, and Quality control. This covers the techniques in analytical, instrumentation like spectrophotometry, chromatography, electrophoresis, electrochemistry, immunoassays and nucleic acid probes. Also covered are liver function tests cardiac profiles, lipid profiles and kidney functions test. Carbohydrates, amino acids and proteins are also covered. There will be three classes a week.

OBJECTIVES

By the end of the course the students will be able to:

1. Describe laboratory safety, employees and employers' responsibilities.
2.  Learn instrumentation in the laboratory
3. Learn techniques
4. Learn body organs, their functions and disease conditions plus laboratory tests for diagnosis.
5. Learn abnormal results
6. Plus introducing the point of care testing.

 

COURSE CONTENT

Week	Activity
1	Introduction to Clinical Chemistry Healthcare and Laboratory safety regulations and quality control measures.
2	Instrumentation: spectrophotometers, chromatography, electrophoresis, electrochemistry, immunoassays.
3	Classification and Description of Proteins, carbohydrates, electrolytes, lipids and Amino Acids, and heme derivatives
4	Pathophysiology of Body Water and Electrolytes, Blood Gases, Acid-Base balance, and their Disorders
5	Organ system Functions:-renal and liver. Their Functions, Diagnostic Tests and diagnosis CAT 1
6	Gastrointestinal Function and Digestive Disease The Pancreas:  Function and Chemical Pathology
7	Clinical Enzymology; isoenzymes and isoforms Diabetes Mellitus – pathogenesis, complications, function tests, change of analyte in disease.
8	Coronary Artery Disease and Disorders of Lipid Metabolism
9	POCT-Point of Care Testing Toxicology Therapeutic Drug Monitoring
10	Tumor Markers – basic concepts and clinical applications. Endocrinology – Thyroid, the Gonads, Adrenal hormones and hypertension, pathological conditions, tests of hypothalamic and pituitary function.
11	CAT 2
12	REVIEW

 

CONTENT

1. Laboratory safety regulations and quality control measures.
2. Heart diseases- common signs and symptoms.

Laboratory

1. Glucose using Spectrophotometer- includes RBS, FBs, GTT, 2 Hours Glucose.
2. Cholesterol and Triglycerides
3. Bun and Creatinine
4. Total Protein. Albumin, and A/G ratio plus protein fractions with lipoprotein
5. Total Bilirubin, Direct and Indirect Bilirubin, Alkaline Phosphatase.
6. Acid Phosphate and PSA.