PURPOSE OF COURSE
This course is for nursing and other students in the Health Sciences. The course covers basic hematology, hemostasis and blood bank.
EXPECTED LEARNING OUTCOMES
The student should be able to:
- Explain the hematopoietic stages of development for the different blood cells.
- Identify blood cell characteristics in developing cells and some altered morphology of cells in pathologic states.
- Explain the function of bone marrow and how and when to obtain and prepare bone marrow samples for hematologic studies.
- Describe the structure and explain the function of red blood cells.
- Describe the characteristics of the main anemias and leukemias.
- Explain what is involved in normal hemostasis.
- Identify the various red blood cell antigens in the blood group systems.
- Explain what is involved in compatibility testing.
- Explain the criteria for donor selection and the procedures involved in donor unit processing.
- Describe the different blood components and their uses.
- Describe the different transfusion reactions and what causes them.
- Perform some routine hematologic procedures.
COURSE DESCRIPTION
The course introduces the production, maturation, and function of normal blood cells; it covers the morphology of red blood cells, white blood cells and platelets, both for the immature and mature cells. Anemia and leukemia are also covered. Normal hemostasis is introduced. This course also introduces blood group antigen systems and some basic blood bank testing. It covers donor selection, donor unit testing, and possible transfusion reactions. Routine laboratory testing in hematology and hemostasis are also dealt with.
COURSE CONTENT
Week One: Introduction to hematology, Blood cell Morphology and Hemopoiesis Bone Marrow
LAB – Laboratory Safety; Microscopy and Cell
Identification.
Week Two: The Red Blood Cell, white Blood cells and Platelets. Evaluation of Blood Cell Morphology.
Week Three: Blood cells counts, RBC indices, Differential counts, ESR
LAB – Manual WBC count; Manual RBC count;
Week Four: Blood cell abnormalities, Staining and Introduction to Anemia.
Week five: Clinical Characteristics of Anemia and Leukemia
LAB - PBF making and staining; Differential count
Test 1
Week six: Hemostasis and coagulation process
Week seven: Fundamentals of Genetics and Immunology for Blood , Blood group systems; ABO/Rh Grouping, AHG Test.
Week Eight: Banking, Compatibility Testing
Week nine: Donor Selection and Component Preparation, Transfusion Reactions
Week Ten: Cat, Tutorials and Assignments
Revision and Final Exam
LABORATORY TOPICS
- Manual white cell count
- Manual red cell count
- Erythrocyte sedimentation rate
- Hematocrit measurement
- Hemoglobin estimation
- Peripheral blood film making, staining and differential count
- Preparation of red cell suspensions
- ABO/Rh Typing
- Teacher: Tyrus Omondi Swaya