THE PURPOSE OF THE COURSE

This course is required for students taking Nursing as a Major. It is design to introduce students to the basic principles underlying immunologic reactions in the body. Classes will be given 2 times a week including a one laboratory session.

 

EXPECTED LEARNING OUTCOMES

At the end of this course, the student should be able to:

  1. Differentiate and specific immunity
  2. Describe the various immune cells, development and maturation
  3. Describe the functions of antibodies
  4. Describe the mechanisms, Cells and factors involved in hypersensitivity and autoimmunity
  5. Describe the application of MHC molecules in terms of clinical transplantation and rejection

 

COURSE DESCRIPTION

This course covers non-specific and specific immunity. Complement systems: proteins activation and biological properties, cells immunity, immunoglobulins and receptors. Antigen antibody interactions, Major Histocompatibility complex, antigens, autoimmunity, immune deficiencies, transplantation and rejection. Prerequisite CLSC 250, BIO245

 

COURSE CONTENT

Week

ACTIVITY

1

Introduction; Terms; Innate physical barriers

2

Innate-Physical barriers; Innate chemical barriers; Innate cellular defence

3

Innate phagocytosis, Innate respiratory burst and ADCC

4

Acquired immunity cells, HR, CMI

CAT 1

5

Complement- Classical, Alternative and Lectin

Summary complement

6

Antibodies, Antigens, Antigen antibody Interactions

7

Vaccination; Major Histocompatibility complex

8

Hypersensitivity

9

Tolerance, Autoimmunity and Immunodeficiency

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