THE PURPOSE OF THE COURSE
This course is required for students taking Nursing as a Major. It is design to introduce students to the basic principles underlying immunologic reactions in the body. Classes will be given 2 times a week including a one laboratory session.
EXPECTED LEARNING OUTCOMES
At the end of this course, the student should be able to:
- Differentiate and specific immunity
- Describe the various immune cells, development and maturation
- Describe the functions of antibodies
- Describe the mechanisms, Cells and factors involved in hypersensitivity and autoimmunity
- Describe the application of MHC molecules in terms of clinical transplantation and rejection
COURSE DESCRIPTION
This course covers non-specific and specific immunity. Complement systems: proteins activation and biological properties, cells immunity, immunoglobulins and receptors. Antigen antibody interactions, Major Histocompatibility complex, antigens, autoimmunity, immune deficiencies, transplantation and rejection. Prerequisite CLSC 250, BIO245
COURSE CONTENT
Week |
ACTIVITY |
1 |
Introduction; Terms; Innate physical barriers |
2 |
Innate-Physical barriers; Innate chemical barriers; Innate cellular defence |
3 |
Innate phagocytosis, Innate respiratory burst and ADCC |
4 |
Acquired immunity cells, HR, CMI CAT 1 |
5 |
Complement- Classical, Alternative and Lectin Summary complement |
6 |
Antibodies, Antigens, Antigen antibody Interactions |
7 |
Vaccination; Major Histocompatibility complex |
8 |
Hypersensitivity |
9 |
Tolerance, Autoimmunity and Immunodeficiency |
- Teacher: Tyrus Omondi Swaya